MASCC: Multicenter Acute Severe Ulcerative Colitis Cohort Study

PI: Joanna Peloquin Melia, MD & Ashwin Anathakrishnan, MD 

This is a large multi-center cohort of patients with acute severe colitis (ASUC) with homogeneously collected detailed longitudinal clinical and laboratory data. To our knowledge, this will be the first of its kind in the United States, and will be a key resource to understand the natural history, risk stratify and optimize therapeutic algorithms for care of patients with ASUC. An optional biospecimen arm of the study can be utilized for translational research into mechanisms of lack of response and development of biomarkers. 

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